The requirements for microbially low-risk products are described in the standard ISO 29621 "Guidelines for the risk assessment and identification of microbiologically low-risk products". 

These are products that, due to their physicochemical properties, inhibit the growth of microorganisms or kill them.
These are products that meet one or more of the following requirements.

• pH-value: <3
• pH-value: >10
• anhydrous products
• alcohol content: >20%
• filling temperature: >65°C
• water activity: <0.75
• solvent-based products
• oxidizing products
• aluminum chlorohydrate content: >25%

Other low-risk products can be identified as part of an individual risk assessment.
For microbiologically low-risk products, a preservative efficacy test is not necessary as part of the safety assessment.